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In fact, miR-99b-5p also targets/inhibits SMARCD1 , a cofactor of active AR , which may also involve in the miR-99b-5p-mediated nuclear translocation of mTOR. live score tes pppk To the best of our knowledge, this is the first report to propose a functional mechanism of miR-99b-5p/AR/mTOR signaling axis in regulating PCa aggressiveness and progression